張硯評 (Chang, Yen-Ping) 助理教授，國立清華大學 教育心理與諮商學系
Wednesday, December 14, 2022
Tuesday, November 8, 2022
性別表演：京劇坤生孟小冬與民國小報
Time:
11/12/2022 08:00 PM PST
11/12/2022 09:00 PM MST
11/12/2022 10:00 PM CST
11/12/2022 11:00 PM EST
11/13/2022 04:00 AM GMT
11/13/2022 05:00 AM CET
11/13/2022 12:00 PM Taiwan
11/12/2022 08:00 PM PST
11/12/2022 09:00 PM MST
11/12/2022 10:00 PM CST
11/12/2022 11:00 PM EST
11/13/2022 04:00 AM GMT
11/13/2022 05:00 AM CET
11/13/2022 12:00 PM Taiwan
報名網址：TYRA Talk 11月12號
研究領域 (Field):
theater, performance studies, history, gender, sexuality, digital humanities
研究子領域 (Sub-field):
East Asian theater (in particular China and Taiwan), Chinese cultural history, Sinophone studies, data analysis
theater, performance studies, history, gender, sexuality, digital humanities
研究子領域 (Sub-field):
East Asian theater (in particular China and Taiwan), Chinese cultural history, Sinophone studies, data analysis
Abstract:
Much of the work to date on Peking opera and gender has paid attention to male actors’ cross-dressing to play women. In contrast, this talk centers on well-known male impersonator Meng Xiaodong (1908–1977), who was recognized as the most qualified successor of the Yu school (Yu pai). Meng Xiaodong’s significance not only lies in her artistic achievements, but also sheds light on the transformation and performativity of gender roles during the 1920s to 1940s. Her art destabilized actors’ dominant positions in theater across the late imperial to Republican eras, while the media reportage surrounding her points to actresses’ continued struggles to escape from normative gender expectations since the late imperial era. Concomitantly, the western-imported novel term, “new women” (xinnüxing or xinfunü), disrupted the existing structure of female sexuality and caused chaos about the actress’ gender roles. Through analyzing tabloid articles surrounding Meng Xiaodong, I begin with an interrogation of the actress’ “body problem,” that is, the assumption that actresses’ bodies were available for the viewing pleasure of patrons and audiences, both on and off the stage. I then scrutinize affective experiences of actresses, patrons, and audiences centering on the problem to crystalize the morphology of Chinese eroticism and examine how the eroticism, in turn, shaped the affective encounters and, even, contributed to the transformation of gender roles. Ultimately, I argue that Meng Xiaodong showcased resistance against Peking opera actors’ fixed performativity of genders in everyday life, further reflecting changes in gender discourses in the Republican era.
Much of the work to date on Peking opera and gender has paid attention to male actors’ cross-dressing to play women. In contrast, this talk centers on well-known male impersonator Meng Xiaodong (1908–1977), who was recognized as the most qualified successor of the Yu school (Yu pai). Meng Xiaodong’s significance not only lies in her artistic achievements, but also sheds light on the transformation and performativity of gender roles during the 1920s to 1940s. Her art destabilized actors’ dominant positions in theater across the late imperial to Republican eras, while the media reportage surrounding her points to actresses’ continued struggles to escape from normative gender expectations since the late imperial era. Concomitantly, the western-imported novel term, “new women” (xinnüxing or xinfunü), disrupted the existing structure of female sexuality and caused chaos about the actress’ gender roles. Through analyzing tabloid articles surrounding Meng Xiaodong, I begin with an interrogation of the actress’ “body problem,” that is, the assumption that actresses’ bodies were available for the viewing pleasure of patrons and audiences, both on and off the stage. I then scrutinize affective experiences of actresses, patrons, and audiences centering on the problem to crystalize the morphology of Chinese eroticism and examine how the eroticism, in turn, shaped the affective encounters and, even, contributed to the transformation of gender roles. Ultimately, I argue that Meng Xiaodong showcased resistance against Peking opera actors’ fixed performativity of genders in everyday life, further reflecting changes in gender discourses in the Republican era.
Tuesday, November 1, 2022
以行為實驗探討人對於勞動量與財富重分配的正當性偏好
Time:
11/05/2022 07:30 PM PDT
11/05/2022 08:30 PM MDT
11/05/2022 09:30 PM CDT
11/05/2022 10:30 PM EDT
11/06/2022 02:30 AM GMT
11/06/2022 03:30 AM CET
11/06/2022 10:30 AM Taiwan
報名網址：TYRA Talk 11月五號
11/05/2022 07:30 PM PDT
11/05/2022 08:30 PM MDT
11/05/2022 09:30 PM CDT
11/05/2022 10:30 PM EDT
11/06/2022 02:30 AM GMT
11/06/2022 03:30 AM CET
11/06/2022 10:30 AM Taiwan
報名網址：TYRA Talk 11月五號
研究領域 (Field):
Political Science
研究子領域 (Sub-field):
Behavioral political economy, Experimental social science, Computational social science
其他關鍵字 (Supplementary keywords):
行為實驗, 財富重分配, 偏好
Political Science
研究子領域 (Sub-field):
Behavioral political economy, Experimental social science, Computational social science
其他關鍵字 (Supplementary keywords):
行為實驗, 財富重分配, 偏好
Abstract:
We investigate three factors considered crucial in assessing the deservingness of a recipient of income redistribution: effort, luck, and need. Individuals rely on effort cues to assess deservingness, but need and effort push deservingness in opposite directions. More effort generally results in lower need. But unlucky individuals can be needy, despite exerting effort. Based on a model of conditional altruism, we design a real-effort experiment with two conditions: one where luck is observable to the redistributor, and one where luck is unobservable. Comparative static predictions derived from the model were pre-registered as hypotheses. When luck is observable, responses to both need and effort are consistent with the predictions of the model, and we observe clearly identifiable types: those who are insensitive to effort and respond only to need, and others who respond exclusively to effort. Without information about luck, however, the effort cue was obscured and the need effect predominated
We investigate three factors considered crucial in assessing the deservingness of a recipient of income redistribution: effort, luck, and need. Individuals rely on effort cues to assess deservingness, but need and effort push deservingness in opposite directions. More effort generally results in lower need. But unlucky individuals can be needy, despite exerting effort. Based on a model of conditional altruism, we design a real-effort experiment with two conditions: one where luck is observable to the redistributor, and one where luck is unobservable. Comparative static predictions derived from the model were pre-registered as hypotheses. When luck is observable, responses to both need and effort are consistent with the predictions of the model, and we observe clearly identifiable types: those who are insensitive to effort and respond only to need, and others who respond exclusively to effort. Without information about luck, however, the effort cue was obscured and the need effect predominated
Sunday, October 23, 2022
Saturday, September 24, 2022
十月份演講
10/08
JupyterHub 迷你工作坊：開放科學的雲端基地
鄭懷傑 (Whyjay Zheng)Postdoc, Department of Statistics, University of California Berkeley
10/15
用神經影像預測經聚焦超音波底視丘切開術治療的帕金森氏病患之術後效果 林素堇 (Sue-Jin Lin), Postdoctoral Researcher, Montreal Neurological Institute, McGill University
可解釋機器學習：理論與應用
Time:
10/29/2022 06:00 PM PDT
10/29/2022 07:00 PM MDT
10/29/2022 08:00 PM CDT
10/29/2022 09:00 PM EDT
10/30/2022 01:00 AM GMT
10/30/2022 02:00 AM CET
10/30/2022 09:00 AM Taiwan
10/29/2022 06:00 PM PDT
10/29/2022 07:00 PM MDT
10/29/2022 08:00 PM CDT
10/29/2022 09:00 PM EDT
10/30/2022 01:00 AM GMT
10/30/2022 02:00 AM CET
10/30/2022 09:00 AM Taiwan
研究領域 (Field):
Computer Science
研究子領域 (Sub-field):
TrustworthyAI, Recommender Systems
其他關鍵字 (Supplementary keywords):
interpretable machine learning; explainable artificial intelligence
Computer Science
研究子領域 (Sub-field):
TrustworthyAI, Recommender Systems
其他關鍵字 (Supplementary keywords):
interpretable machine learning; explainable artificial intelligence
Abstract:
Despite the remarkable achievement of machine learning in various fields, such as music recommendations of Spotify and neural language translation of Google, designing responsible and accountable ML systems remains a significant problem because of the practical requirements of the stakeholders and the regulations in different domains. Interpretable machine learning hereby provides the transparency of the particular decisions made by machine learning systems. The interpretable machine learning tackles the critical problem that humans cannot understand the behaviors of complex machine learning models and how these models arrive at a particular decision. From this perspective, this talk will mainly focus on introducing interpretable machine learning from both theoretical aspects and its applications.
Despite the remarkable achievement of machine learning in various fields, such as music recommendations of Spotify and neural language translation of Google, designing responsible and accountable ML systems remains a significant problem because of the practical requirements of the stakeholders and the regulations in different domains. Interpretable machine learning hereby provides the transparency of the particular decisions made by machine learning systems. The interpretable machine learning tackles the critical problem that humans cannot understand the behaviors of complex machine learning models and how these models arrive at a particular decision. From this perspective, this talk will mainly focus on introducing interpretable machine learning from both theoretical aspects and its applications.
尋找拓樸超導體：量子電腦的新材料
Title:
尋找拓樸超導體：量子電腦的新材料
尋找拓樸超導體：量子電腦的新材料
Time:
10/22/2022 06:00 PM PDT
10/22/2022 07:00 PM MDT
10/22/2022 08:00 PM CDT
10/22/2022 09:00 PM EDT
10/23/2022 02:00 AM BST
10/23/2022 03:00 AM CEST
10/23/2022 09:00 AM Taiwan
10/22/2022 06:00 PM PDT
10/22/2022 07:00 PM MDT
10/22/2022 08:00 PM CDT
10/22/2022 09:00 PM EDT
10/23/2022 02:00 AM BST
10/23/2022 03:00 AM CEST
10/23/2022 09:00 AM Taiwan
研究領域 (Field):
physics
研究子領域 (Sub-field):
condensed matter theory
其他關鍵字 (Supplementary keywords):
Condensed matter theory, topological superconductors, material searches, material design, quantum computation
physics
研究子領域 (Sub-field):
condensed matter theory
其他關鍵字 (Supplementary keywords):
Condensed matter theory, topological superconductors, material searches, material design, quantum computation
Abstract:
超導體是一種有趣的量子材料，在低溫下可以無耗損地傳遞電流。也因為如此，超導體在應用端的潛力備受重視，在過去數十年來一直都是凝態物理研究的主流之一。在各種不同類型的超導體中，「拓樸超導體」 (topological superconductors) 近年來在學界及業界都引起廣泛且深入的研究。這是因為在低維度之下，這種超導體的邊緣存在著一種零維且零能量的「Majorana粒子」。特別的是當兩顆「Majorana粒子」互換位置時，整個量子態能夠留存互換過程歷史的信息，這種粒子也因此被認為能夠作為量子計算中的最小單位。然而，拓樸超導體最先是由理論預測的量子態，真正在實驗中被驗證擁有Majorana粒子的超導材料少之又少，且正確性眾說紛紜。在這個演講中，我會解釋如何結合數學原則及實際的材料理論來預測及設計擁有Majorana粒子的超導材料。
超導體是一種有趣的量子材料，在低溫下可以無耗損地傳遞電流。也因為如此，超導體在應用端的潛力備受重視，在過去數十年來一直都是凝態物理研究的主流之一。在各種不同類型的超導體中，「拓樸超導體」 (topological superconductors) 近年來在學界及業界都引起廣泛且深入的研究。這是因為在低維度之下，這種超導體的邊緣存在著一種零維且零能量的「Majorana粒子」。特別的是當兩顆「Majorana粒子」互換位置時，整個量子態能夠留存互換過程歷史的信息，這種粒子也因此被認為能夠作為量子計算中的最小單位。然而，拓樸超導體最先是由理論預測的量子態，真正在實驗中被驗證擁有Majorana粒子的超導材料少之又少，且正確性眾說紛紜。在這個演講中，我會解釋如何結合數學原則及實際的材料理論來預測及設計擁有Majorana粒子的超導材料。
用神經影像預測經聚焦超音波底視丘切開術治療的帕金森氏病患之術後效果
Speaker:
林素堇 (Sue-Jin Lin), Postdoctoral Researcher, Montreal Neurological Institute, McGill University
林素堇 (Sue-Jin Lin), Postdoctoral Researcher, Montreal Neurological Institute, McGill University
Time:
10/15/2022 12:00 PM PDT
10/15/2022 01:00 PM MDT
10/15/2022 02:00 PM CDT
10/15/2022 03:00 PM EDT
10/15/2022 08:00 PM BST
10/15/2022 09:00 PM CEST
10/16/2022 03:00 AM Taiwan
10/15/2022 12:00 PM PDT
10/15/2022 01:00 PM MDT
10/15/2022 02:00 PM CDT
10/15/2022 03:00 PM EDT
10/15/2022 08:00 PM BST
10/15/2022 09:00 PM CEST
10/16/2022 03:00 AM Taiwan
研究領域 (Field):
Neuroscience
研究子領域 (Sub-field):
Neurology
其他關鍵字 (Supplementary keywords):
Neuroimaging, Precision Medicine, Clinical Cognitive Neuroscience
Neuroscience
研究子領域 (Sub-field):
Neurology
其他關鍵字 (Supplementary keywords):
Neuroimaging, Precision Medicine, Clinical Cognitive Neuroscience
Abstract:
Subthalamotomy using transcranial magnetic resonance-guided focused ultrasound (tcMRgFUS) is a novel and promising treatment for Parkinson’s Disease (PD). In this study, we investigate if baseline brain imaging features can be early predictors of tcMRgFUS-subthalamotomy efficacy, as well as which are post-treatment brain changes associated with the clinical outcomes. Towards this aim, functional and structural neuroimaging and extensive clinical data from thirty-five PD patients enrolled in a double-blind tcMRgFUS-subthalamotomy clinical trial were analysanalyzeded.
Multivariate cross-correlation analysis revealed that the baseline multi-modal imaging data significantly explain (P＜0.005, FWE-corrected) the inter-individual variability in response to treatment. Most predictive features at baseline included neural fluctuations in distributed cortical regions and structural integrity in the putamen and parietal regions. Additionally, a similar multivariate analysis showed that the population variance in clinical improvements is significantly explained (P＜0.001, FWE-corrected) by a distributed network of concurrent functional and structural brain changes in frontotemporal, parietal, occipital, and cerebellar regions, as opposed to local changes in very specific brain regions. Overall, our findings reveal specific quantitative brain signatures highly predictive of tcMRgFUS-subthalamotomy responsiveness in PD. The unanticipated weight of a cortical-subcortical-cerebellar subnetwork in defining clinical outcomes extends the current biological understanding of the mechanisms associated with clinical benefits.
Subthalamotomy using transcranial magnetic resonance-guided focused ultrasound (tcMRgFUS) is a novel and promising treatment for Parkinson’s Disease (PD). In this study, we investigate if baseline brain imaging features can be early predictors of tcMRgFUS-subthalamotomy efficacy, as well as which are post-treatment brain changes associated with the clinical outcomes. Towards this aim, functional and structural neuroimaging and extensive clinical data from thirty-five PD patients enrolled in a double-blind tcMRgFUS-subthalamotomy clinical trial were analysanalyzeded.
Multivariate cross-correlation analysis revealed that the baseline multi-modal imaging data significantly explain (P＜0.005, FWE-corrected) the inter-individual variability in response to treatment. Most predictive features at baseline included neural fluctuations in distributed cortical regions and structural integrity in the putamen and parietal regions. Additionally, a similar multivariate analysis showed that the population variance in clinical improvements is significantly explained (P＜0.001, FWE-corrected) by a distributed network of concurrent functional and structural brain changes in frontotemporal, parietal, occipital, and cerebellar regions, as opposed to local changes in very specific brain regions. Overall, our findings reveal specific quantitative brain signatures highly predictive of tcMRgFUS-subthalamotomy responsiveness in PD. The unanticipated weight of a cortical-subcortical-cerebellar subnetwork in defining clinical outcomes extends the current biological understanding of the mechanisms associated with clinical benefits.
JupyterHub 迷你工作坊：開放科學的雲端基地
Time:
10/08/2022 06:00 PM PDT
10/08/2022 07:00 PM MDT
10/08/2022 08:00 PM CDT
10/08/2022 09:00 PM EDT
10/09/2022 02:00 AM BST
10/09/2022 03:00 AM CEST
10/09/2022 09:00 AM Taiwan
10/08/2022 06:00 PM PDT
10/08/2022 07:00 PM MDT
10/08/2022 08:00 PM CDT
10/08/2022 09:00 PM EDT
10/09/2022 02:00 AM BST
10/09/2022 03:00 AM CEST
10/09/2022 09:00 AM Taiwan
研究領域 (Field):
Earth science, data science
研究子領域 (Sub-field):Earth science, data science
cryosphere science, remote sensing, geophysics, planetary science
其他關鍵字 (Supplementary keywords):
Jupyter, open science, science communication, research, education
Abstract:
科研活動因雲端技術的發展而有了新的實踐方式，全面性的開放科學也成為可能。本次的 Tyra 演講我將以迷你工作坊的形式討論如何以建基在雲端的工具 JupyterHub 實踐不同規模（個人、團隊、社群）與不同目的（研究、教育）的開放科學。 參加本演講不需任何背景知識以及程式設計的技巧，不過如果要在演講時同步存取 JupyterHub 資源，必須要先準備 Google 或是 Microsoft 的帳戶以進行第三方登入 (OAuth)。
西北太平洋海冰變化歷史重建與可能的控制因素
Title:
西北太平洋海冰變化歷史重建與可能的控制因素
西北太平洋海冰變化歷史重建與可能的控制因素
Time:
10/01/2022 08:00 PM PDT
10/01/2022 09:00 PM MDT
10/01/2022 10:00 PM CDT
10/01/2022 11:00 PM EDT
10/02/2022 04:00 AM BST
10/02/2022 05:00 AM CEST
10/02/2022 11:00 AM Taiwan
10/01/2022 08:00 PM PDT
10/01/2022 09:00 PM MDT
10/01/2022 10:00 PM CDT
10/01/2022 11:00 PM EDT
10/02/2022 04:00 AM BST
10/02/2022 05:00 AM CEST
10/02/2022 11:00 AM Taiwan
研究領域 (Field):
Paleoceanography
研究子領域 (Sub-field):
Paleoclimatology
其他關鍵字 (Supplementary keywords):
Marine Geology, Geochemistry, Micropaleontology
Paleoceanography
研究子領域 (Sub-field):
Paleoclimatology
其他關鍵字 (Supplementary keywords):
Marine Geology, Geochemistry, Micropaleontology
Abstract:
海冰的變化藉由大眾媒體的傳送成為環境變遷議題的主要視覺影像之一，但由於高緯度直接觀測不易，人類直到1980年代之後才有機會全天候的觀測海冰的變化，對於海冰作為氣候與生態系統的一部分，我們仍有許多未知之處。本次將分享我們在西北太平洋鄂霍次克海地區重建之過去13萬年來的海冰紀錄，我們發現太陽日照量與溫室氣體作為兩個主要控制的因子，主導了此區域的海冰變化歷史，希望透過古氣候古海洋學的手法，重建過去的歷史，讓我們更多理解地球氣候系統的機制以面對更具挑戰性的未來。
海冰的變化藉由大眾媒體的傳送成為環境變遷議題的主要視覺影像之一，但由於高緯度直接觀測不易，人類直到1980年代之後才有機會全天候的觀測海冰的變化，對於海冰作為氣候與生態系統的一部分，我們仍有許多未知之處。本次將分享我們在西北太平洋鄂霍次克海地區重建之過去13萬年來的海冰紀錄，我們發現太陽日照量與溫室氣體作為兩個主要控制的因子，主導了此區域的海冰變化歷史，希望透過古氣候古海洋學的手法，重建過去的歷史，讓我們更多理解地球氣候系統的機制以面對更具挑戰性的未來。
Thursday, September 8, 2022
日常生活作息對風險偏好之影響
Time:
09/17/2022 05:00 PM PDT
09/17/2022 06:00 PM MDT
09/17/2022 07:00 PM CDT
09/17/2022 08:00 PM EDT
09/18/2022 01:00 AM BST
09/18/2022 02:00 AM CEST
09/18/2022 08:00 AM Taiwan
09/17/2022 05:00 PM PDT
09/17/2022 06:00 PM MDT
09/17/2022 07:00 PM CDT
09/17/2022 08:00 PM EDT
09/18/2022 01:00 AM BST
09/18/2022 02:00 AM CEST
09/18/2022 08:00 AM Taiwan
Field:
psychology
Sub-field:
neuroeconomics
psychology
Sub-field:
neuroeconomics
Abstract:
Environmental states affect our day-to-day emotions and decisions, including our choices under risk and uncertainty. Past studies have found that an unexpected positive outcome, such as a sunny day after a streak of cloudy days, can increase gambling behaviors. To extend these findings with the broader environmental events to more personal daily life activities at a shorter time scale, we performed longitudinal examinations of the correlation between various daily activities and the change of mood and decision of risk within the individual. Our aim is to identify how engagement in different activities could predict the temporal change in mood and risk preferences. In the talk, I will present data showing how the amount of a particular activity spent last week correlates with the risk attitude-related variables. Among all activities data we had gathered, our finding suggests that subjects have less negative emotion and become more risk-tolerant with more sleep time.
Environmental states affect our day-to-day emotions and decisions, including our choices under risk and uncertainty. Past studies have found that an unexpected positive outcome, such as a sunny day after a streak of cloudy days, can increase gambling behaviors. To extend these findings with the broader environmental events to more personal daily life activities at a shorter time scale, we performed longitudinal examinations of the correlation between various daily activities and the change of mood and decision of risk within the individual. Our aim is to identify how engagement in different activities could predict the temporal change in mood and risk preferences. In the talk, I will present data showing how the amount of a particular activity spent last week correlates with the risk attitude-related variables. Among all activities data we had gathered, our finding suggests that subjects have less negative emotion and become more risk-tolerant with more sleep time.
Thursday, August 4, 2022
2022海外研究所申請指導計畫-系列演講
海外研究所申請流程有哪些？我該如何撰寫申請文件？ 一起來聽聽學長姐的經驗談吧！
【指導計畫 02】北美博士班申請流程與技巧
臺灣08/21 （日）早上9點
王孟仁 助理教授, University of Utah 核工
黃炤愷 博士生, Arizona State University 社工
【指導計畫 01】歐洲博士班申請流程與技巧
臺灣08/14 （日）晚上9點
張櫂杬 博士生, Technische Universität Dresdenn醫工
曾靖容 博士生, Université catholique de Louvain 經濟
臺灣08/14 （日）晚上9點
張櫂杬 博士生, Technische Universität Dresdenn醫工
曾靖容 博士生, Université catholique de Louvain 經濟
【指導計畫 02】北美博士班申請流程與技巧
臺灣08/21 （日）早上9點
王孟仁 助理教授, University of Utah 核工
黃炤愷 博士生, Arizona State University 社工
【指導計畫 03】CV and SOP撰寫技巧
臺灣08/28（日）早上9點
丁艾竹 助理教授, University of Georgia 教育
吳嘉恩 博士生, Indiana University Bloomington 公共管理
盧彥君 博士後, Boston Children's Hospital / Massachusetts Institute of Technology 生物醫學工程
孫楷惠 業界就職, Gilead Sciences 細胞分子生物學
註1：
此為Mentor-Mentee Program先行系列演講，如有意願再參加之後的「一對一 PhD 申請的mentoring」(Mentor-Mentee Program)，報名並出席至少【指導計畫 01】 + 【指導計畫 03】 或 【指導計畫 02】 + 【指導計畫 03】，將享有優先配對Mentor的機會！
註2：
以上時間皆為台灣時間。請留意時差，並換算正確時間
報名參見: Project Tyra
此為Mentor-Mentee Program先行系列演講，如有意願再參加之後的「一對一 PhD 申請的mentoring」(Mentor-Mentee Program)，報名並出席至少【指導計畫 01】 + 【指導計畫 03】 或 【指導計畫 02】 + 【指導計畫 03】，將享有優先配對Mentor的機會！
註2：
以上時間皆為台灣時間。請留意時差，並換算正確時間
報名參見: Project Tyra
Tuesday, June 21, 2022
八月份演講
陳泰延(Tai-Yen Chen), Assistant professor, University of Houston
【指導計畫 02】北美博士班申請流程與技巧
臺灣08/21 （日）早上9點
王孟仁 助理教授, University of Utah 核工
黃炤愷 博士生, Arizona State University 社工
【指導計畫 03】CV and SOP撰寫技巧
臺灣08/28（日）早上9點
丁艾竹 助理教授, University of Georgia 教育
吳嘉恩 博士生, Indiana University Bloomington 公共管理
盧彥君 博士後, Boston Children's Hospital / Massachusetts Institute of Technology 生物醫學工程
孫楷惠 業界就職, Gilead Sciences 細胞分子生物學
2022海外研究所申請指導計畫-系列演講
【指導計畫 01】歐洲博士班申請流程與技巧
臺灣08/14 （日）晚上9點
張櫂杬 博士生, Technische Universität Dresdenn醫工
曾靖容 博士生, Université catholique de Louvain 經濟
臺灣08/14 （日）晚上9點
張櫂杬 博士生, Technische Universität Dresdenn醫工
曾靖容 博士生, Université catholique de Louvain 經濟
【指導計畫 02】北美博士班申請流程與技巧
臺灣08/21 （日）早上9點
王孟仁 助理教授, University of Utah 核工
黃炤愷 博士生, Arizona State University 社工
【指導計畫 03】CV and SOP撰寫技巧
臺灣08/28（日）早上9點
丁艾竹 助理教授, University of Georgia 教育
吳嘉恩 博士生, Indiana University Bloomington 公共管理
盧彥君 博士後, Boston Children's Hospital / Massachusetts Institute of Technology 生物醫學工程
孫楷惠 業界就職, Gilead Sciences 細胞分子生物學
How to have a successful Ph.D. career: for senior PhD Student
Time:
08/06/2022 12:00 PM PDT
08/06/2022 01:00 PM MDT
08/06/2022 02:00 PM CDT
08/06/2022 03:00 PM EDT
08/06/2022 08:00 PM BST
08/06/2022 09:00 PM CEST
08/07/2022 03:00 AM Taiwan
08/06/2022 12:00 PM PDT
08/06/2022 01:00 PM MDT
08/06/2022 02:00 PM CDT
08/06/2022 03:00 PM EDT
08/06/2022 08:00 PM BST
08/06/2022 09:00 PM CEST
08/07/2022 03:00 AM Taiwan
研究領域 (Field):
Biophysics
研究子領域 (Sub-field):
Single-molecule Biophysics
其他關鍵字 (Supplementary keywords):
Cu, homeostasis, trafficking, FRET, oligomer
Biophysics
研究子領域 (Sub-field):
Single-molecule Biophysics
其他關鍵字 (Supplementary keywords):
Cu, homeostasis, trafficking, FRET, oligomer
Abstract:
Being a Ph.D. candidate, you officially enter the second half of your Ph.D. journey. At this stage, you should have mastered all technical skills and have good knowledge of your field. This seminar will discuss the general two-year plan before your graduation. Specifically, we will focus on working with your advisor to convert your research effort into scientific articles efficiently. We will also discuss general approaches to building professional connections for postdoctoral or industrial job opportunities.
Being a Ph.D. candidate, you officially enter the second half of your Ph.D. journey. At this stage, you should have mastered all technical skills and have good knowledge of your field. This seminar will discuss the general two-year plan before your graduation. Specifically, we will focus on working with your advisor to convert your research effort into scientific articles efficiently. We will also discuss general approaches to building professional connections for postdoctoral or industrial job opportunities.
Monday, June 20, 2022
073022 How to have a successful Ph.D. career: for junior PhD Student
Time:
07/30/2022 07:00 PM PDT
07/30/2022 08:00 PM MDT
07/30/2022 09:00 PM CDT
07/30/2022 10:00 PM EDT
07/31/2022 03:00 AM BST
07/31/2022 04:00 AM CEST
07/31/2022 10:00 AM Taiwan
07/30/2022 07:00 PM PDT
07/30/2022 08:00 PM MDT
07/30/2022 09:00 PM CDT
07/30/2022 10:00 PM EDT
07/31/2022 03:00 AM BST
07/31/2022 04:00 AM CEST
07/31/2022 10:00 AM Taiwan
研究領域 (Field):
Materials Science
研究子領域 (Sub-field):
Photonics and Radiative heat transfer
其他關鍵字 (Supplementary keywords):
Wearable heat management, Building energy efficiency, Electrochemically tunable materials
Materials Science
研究子領域 (Sub-field):
Photonics and Radiative heat transfer
其他關鍵字 (Supplementary keywords):
Wearable heat management, Building energy efficiency, Electrochemically tunable materials
Abstract:
I will share my personal view from various angles to hopefully help junior PhD students stay on the right track. Here are a few subtopics that will be covered: (1)如何找adviser (2)第一年要做的事 (3) 衡量自己與實驗室,老師的fit
I will share my personal view from various angles to hopefully help junior PhD students stay on the right track. Here are a few subtopics that will be covered: (1)如何找adviser (2)第一年要做的事 (3) 衡量自己與實驗室,老師的fit
072322 用單體複形做網絡的資料分析
Time:
07/23/2022 06:00 PM PDT
07/23/2022 07:00 PM MDT
07/23/2022 08:00 PM CDT
07/23/2022 09:00 PM EDT
07/24/2022 02:00 AM BST
07/24/2022 03:00 AM CEST
07/24/2022 09:00 AM Taiwan
07/23/2022 06:00 PM PDT
07/23/2022 07:00 PM MDT
07/23/2022 08:00 PM CDT
07/23/2022 09:00 PM EDT
07/24/2022 02:00 AM BST
07/24/2022 03:00 AM CEST
07/24/2022 09:00 AM Taiwan
研究領域 (Field):
computer science,physics
研究子領域 (Sub-field):
complex systems, applied topology, interdisciplinary physics
其他關鍵字 (Supplementary keywords):
simplicial complex, recursive algorithm, NP-hard problem, network structure, combinatorics
computer science,physics
研究子領域 (Sub-field):
complex systems, applied topology, interdisciplinary physics
其他關鍵字 (Supplementary keywords):
simplicial complex, recursive algorithm, NP-hard problem, network structure, combinatorics
Abstract:
許多複雜系統可以用網絡模型來描述，例如人如何達成共識，或是昆蟲與花的授粉行為等。如果系統的單元是倆倆相互作用，我們可以用數學的圖來描述。如果系統的作用牽涉到超過兩個單元，我們可以用「超圖」或者是「單體複形」來描述。在這個演講中，我會說明什麼時候該選擇什麼模型。然後，我會把焦點集中在單體複形以及和它相關的組合學問題，叫 "simpliciality testing"。這個問題問說，如果給定兩組整數序列，我們能不能用它們建構出一個單體複形，使其「節點度分佈」和「面尺寸分佈」分別對應到那兩個序列。雖然有人證明該問題是 NP-complete，但我們發現一個很有效的遞迴演算法。因為這個發現，我們可以建構統計上的假設模型，分析未知數據的拓樸結構是否有顯著性。此演講的內容建立在這篇論文上：Yen, Phys. Rev. E 104, L042303 (2021).
許多複雜系統可以用網絡模型來描述，例如人如何達成共識，或是昆蟲與花的授粉行為等。如果系統的單元是倆倆相互作用，我們可以用數學的圖來描述。如果系統的作用牽涉到超過兩個單元，我們可以用「超圖」或者是「單體複形」來描述。在這個演講中，我會說明什麼時候該選擇什麼模型。然後，我會把焦點集中在單體複形以及和它相關的組合學問題，叫 "simpliciality testing"。這個問題問說，如果給定兩組整數序列，我們能不能用它們建構出一個單體複形，使其「節點度分佈」和「面尺寸分佈」分別對應到那兩個序列。雖然有人證明該問題是 NP-complete，但我們發現一個很有效的遞迴演算法。因為這個發現，我們可以建構統計上的假設模型，分析未知數據的拓樸結構是否有顯著性。此演講的內容建立在這篇論文上：Yen, Phys. Rev. E 104, L042303 (2021).
071622 Application of Machine-Learning on the Multi-Parameter Observations in the Earth's Upper Atmosphere
Title:
Application of Machine-Learning on the Multi-Parameter Observations in the Earth's Upper Atmosphere
Application of Machine-Learning on the Multi-Parameter Observations in the Earth's Upper Atmosphere
Time:
07/16/2022 06:00 PM PDT
07/16/2022 07:00 PM MDT
07/16/2022 06:00 PM PDT
07/16/2022 07:00 PM MDT
07/16/2022 08:00 PM CDT
07/16/2022 09:00 PM EDT
07/16/2022 09:00 PM EDT
07/17/2022 02:00 AM BST
07/17/2022 03:00 AM CEST
07/17/2022 09:00 AM Taiwan
07/17/2022 09:00 AM Taiwan
Field:
Physics
Physics
Sub-field:
Space Physics
Space Physics
為配合本研究發表時程，本次錄影將延遲上傳
Abstract:
The Ionospheric CONnection Explorer (ICON) spacecraft launched in the deep solar minimum of late 2019 and joined the troop of Earth’s upper atmosphere monitors including Global-scale Observations of the Limb and Disk (GOLD). Due to the spatial and temporal entanglement and limited coverage of data, integrating the space-borne observations from different platforms is a challenging task and usually requires support from whole atmospheric modeling. Integrating the observations from both ICON and GOLD provides a broader and more comprehensive view of the upper atmosphere, spatially and temporally. Taking the advantages of the rapid development of artificial intelligence, the applications of the machine learning algorithms and neural networks on space sciences is foreseeable.
The Ionospheric CONnection Explorer (ICON) spacecraft launched in the deep solar minimum of late 2019 and joined the troop of Earth’s upper atmosphere monitors including Global-scale Observations of the Limb and Disk (GOLD). Due to the spatial and temporal entanglement and limited coverage of data, integrating the space-borne observations from different platforms is a challenging task and usually requires support from whole atmospheric modeling. Integrating the observations from both ICON and GOLD provides a broader and more comprehensive view of the upper atmosphere, spatially and temporally. Taking the advantages of the rapid development of artificial intelligence, the applications of the machine learning algorithms and neural networks on space sciences is foreseeable.
070922 高層大氣風場估計以及其與太空天氣相關性
Time:
07/09/2022 06:00 PM PDT
07/09/2022 07:00 PM MDT
07/09/2022 08:00 PM CDT
07/09/2022 09:00 PM EDT
07/10/2022 02:00 AM BST
07/10/2022 03:00 AM CEST
07/10/2022 09:00 AM Taiwan
07/09/2022 06:00 PM PDT
07/09/2022 07:00 PM MDT
07/09/2022 08:00 PM CDT
07/09/2022 09:00 PM EDT
07/10/2022 02:00 AM BST
07/10/2022 03:00 AM CEST
07/10/2022 09:00 AM Taiwan
研究領域 (Field):
Ionospheric physics
研究子領域 (Sub-field):
Ionospheric electrodynamics, estimation
其他關鍵字 (Supplementary keywords):
ionosphere, electrodynamics, magnetometers, estimation
Ionospheric physics
研究子領域 (Sub-field):
Ionospheric electrodynamics, estimation
其他關鍵字 (Supplementary keywords):
ionosphere, electrodynamics, magnetometers, estimation
Abstract:
太空包含距地表約100至600公里的大氣層，即所謂電離層。其大氣組成為電漿與非帶電粒子，並有強烈逐日變化。當無線電波經此區與電漿作用，可能誘發閃爍現象並影響其接收，因此近年來太空天氣預報逐漸受到軍方重視。過去研究顯示：電離層電漿分佈與電離層底層全球風場分佈相互影響並有其相關性。由於高空資料稀疏性，目前要得到全球電漿與風場分佈通常需要累積約數十日至數月觀測，此方式可能影響其逐日變化強度判斷。本研究透過結合觀測與模式，估計全球風場每小時變化，並提供全新的角度檢驗過去電離層逐日變化理論。其結果顯示電漿分佈之每日變化可能部分來自於低層大氣的影響，與過去理論相符。
太空包含距地表約100至600公里的大氣層，即所謂電離層。其大氣組成為電漿與非帶電粒子，並有強烈逐日變化。當無線電波經此區與電漿作用，可能誘發閃爍現象並影響其接收，因此近年來太空天氣預報逐漸受到軍方重視。過去研究顯示：電離層電漿分佈與電離層底層全球風場分佈相互影響並有其相關性。由於高空資料稀疏性，目前要得到全球電漿與風場分佈通常需要累積約數十日至數月觀測，此方式可能影響其逐日變化強度判斷。本研究透過結合觀測與模式，估計全球風場每小時變化，並提供全新的角度檢驗過去電離層逐日變化理論。其結果顯示電漿分佈之每日變化可能部分來自於低層大氣的影響，與過去理論相符。
070222 Mission ACE: Apophis Close Encounter
Time:
07/02/2022 07:30 PM PDT
07/02/2022 08:30 PM MDT
07/02/2022 09:30 PM CDT
07/02/2022 10:30 PM EDT
07/03/2022 03:30 AM BST
07/03/2022 04:30 AM CEST
07/03/2022 10:30 AM Taiwan
07/02/2022 07:30 PM PDT
07/02/2022 08:30 PM MDT
07/02/2022 09:30 PM CDT
07/02/2022 10:30 PM EDT
07/03/2022 03:30 AM BST
07/03/2022 04:30 AM CEST
07/03/2022 10:30 AM Taiwan
研究領域 (Field):
physics
研究子領域 (Sub-field):
planetary science
physics
研究子領域 (Sub-field):
planetary science
Abstract:
On April 13th, 2029, a Potential Hazardous Asteroid (PHA) 99942 Apophis will visit Earth at a distance about 36700 ± 9000 km, which is almost the altitude of geosynchronous satellites. Such a close approach of an asteroid will provide an extraordinary opportunity to study a PHA in great detail and to raise public awareness of planetary defense. Here we propose a mission concept “ACE (Apophis Close Encounter)” which aims to rendezvous with Apophis prior to its 2029 flyby and to shepherd the asteroid for several months to investigate its possible evolution induced by the tidal force of Earth. The mission is scheduled to launch in August 2028 and expected to end in late August or early September of 2029 with a lifetime of around 280 days.
On April 13th, 2029, a Potential Hazardous Asteroid (PHA) 99942 Apophis will visit Earth at a distance about 36700 ± 9000 km, which is almost the altitude of geosynchronous satellites. Such a close approach of an asteroid will provide an extraordinary opportunity to study a PHA in great detail and to raise public awareness of planetary defense. Here we propose a mission concept “ACE (Apophis Close Encounter)” which aims to rendezvous with Apophis prior to its 2029 flyby and to shepherd the asteroid for several months to investigate its possible evolution induced by the tidal force of Earth. The mission is scheduled to launch in August 2028 and expected to end in late August or early September of 2029 with a lifetime of around 280 days.
Monday, May 30, 2022
Saturday, May 28, 2022
062522 Social Safety Net Features in East Asia: A comparative analyses using the model family approach
Title:
Social Safety Net Features in East Asia: A comparative analyses using the model family approach
Social Safety Net Features in East Asia: A comparative analyses using the model family approach
Time:
06/25/2022 06:30 PM PDT
06/25/2022 07:30 PM MDT
06/25/2022 08:30 PM CDT
06/25/2022 09:30 PM EDT
06/26/2022 02:30 AM BST
06/26/2022 03:30 AM CEST
06/26/2022 09:30 AM Taiwan
06/25/2022 06:30 PM PDT
06/25/2022 07:30 PM MDT
06/25/2022 08:30 PM CDT
06/25/2022 09:30 PM EDT
06/26/2022 02:30 AM BST
06/26/2022 03:30 AM CEST
06/26/2022 09:30 AM Taiwan
研究領域 (Field):
Social Policy
研究子領域 (Sub-field)::
Poverty; Social Welfare Policies
Social Policy
研究子領域 (Sub-field)::
Poverty; Social Welfare Policies
Abstract:
East Asian social welfare has been described as productivist, where social policies are subordinate to economic development. However, existing East Asian comparative studies often focus on a few selected social policies and seldom examine welfare programs as a bundle. We contribute to the depiction of divergent features of East Asian safety nets by welfare content (generosity, coverage, protective vs. productive, and work incentives) and welfare outcomes (poverty reduction and redistribution) in mainland China, Hong Kong, Japan, Singapore, South Korea, and Taiwan.
We collected model family data before and during the COVID-19 pandemic and analyzed the data through descriptive statistics and regression models. We found that Taiwan and Japan have more generous welfare systems in reducing poverty and redistributing income, while Korea has a less generous system and focuses on productive programs; Hong Kong is catching up with the aforementioned societies through adopting generous protective programs; Singapore offers wide coverage and work incentives for low-income families yet lags behind in generosity; and China appears to be a laggard of welfare provision in the region. Our findings reveal heterogeneity within East Asian welfare system, and our synthesis of welfare features using model family data exemplifies a promising strategy in conducting comparative research in regions with limited comparable data.
East Asian social welfare has been described as productivist, where social policies are subordinate to economic development. However, existing East Asian comparative studies often focus on a few selected social policies and seldom examine welfare programs as a bundle. We contribute to the depiction of divergent features of East Asian safety nets by welfare content (generosity, coverage, protective vs. productive, and work incentives) and welfare outcomes (poverty reduction and redistribution) in mainland China, Hong Kong, Japan, Singapore, South Korea, and Taiwan.
We collected model family data before and during the COVID-19 pandemic and analyzed the data through descriptive statistics and regression models. We found that Taiwan and Japan have more generous welfare systems in reducing poverty and redistributing income, while Korea has a less generous system and focuses on productive programs; Hong Kong is catching up with the aforementioned societies through adopting generous protective programs; Singapore offers wide coverage and work incentives for low-income families yet lags behind in generosity; and China appears to be a laggard of welfare provision in the region. Our findings reveal heterogeneity within East Asian welfare system, and our synthesis of welfare features using model family data exemplifies a promising strategy in conducting comparative research in regions with limited comparable data.
061822 From Substrate to Surface: Dissolved Oxygen Transfer and Sediment Suspension in Environmental Vegetated Flows
Title:
From Substrate to Surface: Dissolved Oxygen Transfer and Sediment Suspension in Environmental Vegetated Flows
From Substrate to Surface: Dissolved Oxygen Transfer and Sediment Suspension in Environmental Vegetated Flows
Time:
06/18/2022 06:00 PM PDT
06/18/2022 07:00 PM MDT
06/18/2022 08:00 PM CDT
06/18/2022 09:00 PM EDT
06/19/2022 02:00 AM BST
06/19/2022 03:00 AM CEST
06/19/2022 09:00 AM Taiwan
06/18/2022 06:00 PM PDT
06/18/2022 07:00 PM MDT
06/18/2022 08:00 PM CDT
06/18/2022 09:00 PM EDT
06/19/2022 02:00 AM BST
06/19/2022 03:00 AM CEST
06/19/2022 09:00 AM Taiwan
研究領域 (Field):
Civil and Environmental Engineering
研究子領域 (Sub-field):
Environmental Fluid Mechanics, Hydraulics, Environmental Turbulence
其他關鍵字 (Supplementary keywords):
Turbulent Mixing, Interfacial Gas Transfer, Fluid-structure Interaction, Ecohydraulics, Sediment Transport
Civil and Environmental Engineering
研究子領域 (Sub-field):
Environmental Fluid Mechanics, Hydraulics, Environmental Turbulence
其他關鍵字 (Supplementary keywords):
Turbulent Mixing, Interfacial Gas Transfer, Fluid-structure Interaction, Ecohydraulics, Sediment Transport
Abstract:
Turbulence generated by aquatic vegetation plays a vital role in the interfacial transfer process at the air-water interface and sediment-water interface (AWI and SWI), impacting the dissolved oxygen (DO) level, a key indicator of water quality for aquatic ecosystems. This research investigates how flow-vegetation interactions affect suspended sediment dynamics and the interfacial transfer process across sediment-water-air interfaces in unidirectional vegetated flows. A series of laboratory experiments in a unidirectional recirculating flume with simulated rigid vegetation and a sediment bed was conducted to investigate the influence of vegetation under different submergence ratios and plant densities. The experimental result shows how different scales of vegetation-generated turbulence affect the interfacial gas transfer rate at different submergence ratios and array densities. This study is expected to provide critical insight for future studies on water quality management and ecosystem restoration in natural vegetated water environments such as lakes, rivers, and wetlands.
Turbulence generated by aquatic vegetation plays a vital role in the interfacial transfer process at the air-water interface and sediment-water interface (AWI and SWI), impacting the dissolved oxygen (DO) level, a key indicator of water quality for aquatic ecosystems. This research investigates how flow-vegetation interactions affect suspended sediment dynamics and the interfacial transfer process across sediment-water-air interfaces in unidirectional vegetated flows. A series of laboratory experiments in a unidirectional recirculating flume with simulated rigid vegetation and a sediment bed was conducted to investigate the influence of vegetation under different submergence ratios and plant densities. The experimental result shows how different scales of vegetation-generated turbulence affect the interfacial gas transfer rate at different submergence ratios and array densities. This study is expected to provide critical insight for future studies on water quality management and ecosystem restoration in natural vegetated water environments such as lakes, rivers, and wetlands.
061122 無意識訊息處理的複雜性：我們還要意識做什麼？
Title:
無意識訊息處理的複雜性：我們還要意識做什麼？
無意識訊息處理的複雜性：我們還要意識做什麼？
Time:
06/11/2022 06:00 PM PDT
06/11/2022 07:00 PM MDT
06/11/2022 08:00 PM CDT
06/11/2022 09:00 PM EDT
06/12/2022 02:00 AM BST
06/12/2022 03:00 AM CEST
06/12/2022 09:00 AM Taiwan
06/11/2022 06:00 PM PDT
06/11/2022 07:00 PM MDT
06/11/2022 08:00 PM CDT
06/11/2022 09:00 PM EDT
06/12/2022 02:00 AM BST
06/12/2022 03:00 AM CEST
06/12/2022 09:00 AM Taiwan
研究領域 (Field):
Experimental Psychology
研究子領域 (Sub-field):
Cognition and Perception
其他關鍵字 (Supplementary keywords):
Consciousness; Attention; Language
Experimental Psychology
研究子領域 (Sub-field):
Cognition and Perception
其他關鍵字 (Supplementary keywords):
Consciousness; Attention; Language
Abstract:
我們時時刻刻都意識到外在的世界嗎？知覺心理學提供許多證據，在在暗示我們能夠意識到的外在世界十分受限。那麼，這些我們沒有意識到的訊息是否通通被大腦忽略了呢？過去幾年我們的研究提供了一些線索，顯示看似複雜、高階的無意識訊息，卻能被大腦處理而進一步影響我們的行為。演講的最後我想談談，如果無意識處理可以如此複雜，意識的功能究竟是什麼？
我們時時刻刻都意識到外在的世界嗎？知覺心理學提供許多證據，在在暗示我們能夠意識到的外在世界十分受限。那麼，這些我們沒有意識到的訊息是否通通被大腦忽略了呢？過去幾年我們的研究提供了一些線索，顯示看似複雜、高階的無意識訊息，卻能被大腦處理而進一步影響我們的行為。演講的最後我想談談，如果無意識處理可以如此複雜，意識的功能究竟是什麼？
Sunday, May 15, 2022
五月演講
Title:
五月演講
五月演講
5/21 吳彥蓉 (Yen-Jung Wu)
Application of Machine-Learning on the Multi-Parameter Observations in the Earth’s Upper Atmosphere
Application of Machine-Learning on the Multi-Parameter Observations in the Earth’s Upper Atmosphere
5/28 徐瑋澤 (Wei-Tse Hsu)
Developing computational screening methods for identifying O-glycosylated insulin analogs with improved properties for oral delivery
Developing computational screening methods for identifying O-glycosylated insulin analogs with improved properties for oral delivery
Sunday, May 1, 2022
052822 Developing molecular dynamics-based screening methods for identifying O-glycosylated insulin analogs with enhanced proteolytic stability and monomeric propensity
Title:
Developing molecular dynamics-based screening methods for identifying O-glycosylated insulin analogs with enhanced proteolytic stability and monomeric propensity
Developing molecular dynamics-based screening methods for identifying O-glycosylated insulin analogs with enhanced proteolytic stability and monomeric propensity
Time:
05/28/2022 07:00 PM PDT
05/28/2022 08:00 PM MDT
05/28/2022 07:00 PM PDT
05/28/2022 08:00 PM MDT
05/28/2022 09:00 PM CDT
05/28/2022 10:00 PM EDT
05/28/2022 10:00 PM EDT
05/29/2022 03:00 AM BST
05/29/2022 04:00 AM CEST
05/29/2022 10:00 AM Taiwan
05/29/2022 10:00 AM Taiwan
Field:
Biophysics, computational chemistry
Biophysics, computational chemistry
Sub-field:
molecular dynamics
Supplementary keywords:
molecular dynamics, insulin, O-glycosylation, protein degradation, protein design
molecular dynamics
Supplementary keywords:
molecular dynamics, insulin, O-glycosylation, protein degradation, protein design
Abstract:
In the United States, over 7 million people use insulin as a peptide drug to treat diabetes given its ability to promote the glucose absorption from the blood into liver. While oral insulin drugs are highly desirable due to their non-invasive nature, their development is limited by their susceptibility to the enzymes in the gastrointestinal tract and poor permeability through the intestinal epithelium upon dimerization. Recent experimental studies have revealed that certain O-linked glycosylation patterns could enhance insulin’s proteolytic stability and reduce its dimerization propensity, but the understanding of such phenomena at the molecular level is still evasive. In addition, the enormous efforts required for chemical synthesis and characterization make fast screening of insulin glycoform candidates nearly impossible.
To address this challenge, we propose and test several structural determinants that could potentially enhance insulin’s proteolytic stability and monomeric propensity. We used these as the metrics to assess the properties of interest from 10-microsecond aggregate molecular dynamics of each of 12 targeted insulin glyco-variants from multiple wild-type crystal structures. We found that glycan-involved hydrogen bonds and glycan-dimer occlusion were useful metrics predicting the proteolytic stability and dimerization propensity of insulin, as was in part the solvent accessible surface area of proteolytic sites, while other plausible metrics were not generally predictive. This work helps better explain how O-linked glycosylation influences the proteolytic stability and monomeric propensity of insulin, illuminating a path towards rational molecular design of insulin glycoforms.
In the United States, over 7 million people use insulin as a peptide drug to treat diabetes given its ability to promote the glucose absorption from the blood into liver. While oral insulin drugs are highly desirable due to their non-invasive nature, their development is limited by their susceptibility to the enzymes in the gastrointestinal tract and poor permeability through the intestinal epithelium upon dimerization. Recent experimental studies have revealed that certain O-linked glycosylation patterns could enhance insulin’s proteolytic stability and reduce its dimerization propensity, but the understanding of such phenomena at the molecular level is still evasive. In addition, the enormous efforts required for chemical synthesis and characterization make fast screening of insulin glycoform candidates nearly impossible.
To address this challenge, we propose and test several structural determinants that could potentially enhance insulin’s proteolytic stability and monomeric propensity. We used these as the metrics to assess the properties of interest from 10-microsecond aggregate molecular dynamics of each of 12 targeted insulin glyco-variants from multiple wild-type crystal structures. We found that glycan-involved hydrogen bonds and glycan-dimer occlusion were useful metrics predicting the proteolytic stability and dimerization propensity of insulin, as was in part the solvent accessible surface area of proteolytic sites, while other plausible metrics were not generally predictive. This work helps better explain how O-linked glycosylation influences the proteolytic stability and monomeric propensity of insulin, illuminating a path towards rational molecular design of insulin glycoforms.
Sunday, April 24, 2022
043022 Cognitive Hierarchies in Extensive Form Games
Title:
Cognitive Hierarchies in Extensive Form Games
Cognitive Hierarchies in Extensive Form Games
Time:
04/30/2022 01:00 PM PDT
04/30/2022 02:00 PM MDT
04/30/2022 03:00 PM CDT
04/30/2022 04:00 PM EDT
05/01/2022 07:00 AM BST
05/01/2022 10:00 PM CEST
05/01/2022 04:00 AM Taiwan
04/30/2022 01:00 PM PDT
04/30/2022 02:00 PM MDT
04/30/2022 03:00 PM CDT
04/30/2022 04:00 PM EDT
05/01/2022 07:00 AM BST
05/01/2022 10:00 PM CEST
05/01/2022 04:00 AM Taiwan
Keywords:
Economics, Behavioral Game Theory, Experimental Economics, Cognitive Hierarchy, Extensive Form Games, Learning, Centipede Game
Economics, Behavioral Game Theory, Experimental Economics, Cognitive Hierarchy, Extensive Form Games, Learning, Centipede Game
Abstract:
The cognitive hierarchy (CH) approach posits that players in a game are heterogeneous with respect to levels of strategic sophistication. A level-k player believes all other players in the game have lower levels of sophistication distributed from 0 to k-1, and these beliefs correspond to the truncated distribution of a “true” distribution of levels. We extend the CH framework to extensive form games, where these initial beliefs over lower levels are updated as the history of play in the game unfolds, providing information to players about other players’ levels of sophistication. For a class of centipede games with a linearly increasing pie, we fully characterize the dynamic CH solution and show that it leads to the game terminating earlier than in the static CH solution for the centipede game in reduced normal form.
The cognitive hierarchy (CH) approach posits that players in a game are heterogeneous with respect to levels of strategic sophistication. A level-k player believes all other players in the game have lower levels of sophistication distributed from 0 to k-1, and these beliefs correspond to the truncated distribution of a “true” distribution of levels. We extend the CH framework to extensive form games, where these initial beliefs over lower levels are updated as the history of play in the game unfolds, providing information to players about other players’ levels of sophistication. For a class of centipede games with a linearly increasing pie, we fully characterize the dynamic CH solution and show that it leads to the game terminating earlier than in the static CH solution for the centipede game in reduced normal form.
Wednesday, April 20, 2022
042422 以跨文化溝通為導向的華語教材設計
Title:
以跨文化溝通為導向的華語教材設計
以跨文化溝通為導向的華語教材設計
Time:
04/24/2022 05:00 AM PDT
04/24/2022 06:00 AM MDT
04/24/2022 07:00 AM CDT
04/24/2022 08:00 AM EDT
04/24/2022 01:00 PM BST
04/24/2022 02:00 PM CEST
04/24/2022 08:00 PM Taiwan
04/24/2022 05:00 AM PDT
04/24/2022 06:00 AM MDT
04/24/2022 07:00 AM CDT
04/24/2022 08:00 AM EDT
04/24/2022 01:00 PM BST
04/24/2022 02:00 PM CEST
04/24/2022 08:00 PM Taiwan
Keywords:
華語二語教學 Teaching Chinese as a second language , 跨文化溝通Intercultural Communication,華語學習教材設計Material Development for Teaching Chinese as a Second Language, 華語教學史Early Chinese Teaching/Learning History, 跨文化溝通Intercultural Communication, 華語教學Teaching Chinese as a second language, 教材設計Textbook Design
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Abstract:
二語學習除了主要的目標語（target language）語言本體的學習，也應學習目標語的文化（target language culture）。因為跨文化的溝通交際是立基於語言和文化的理解，缺乏任何一項，都可能造成溝通交際的阻礙或誤解。
有別於一般華語教材以語言本體為主要學習目標，本文以目標語地--臺灣的外籍生跨文化溝通的需求為教材設計的依據，採用質化分析與文獻探討的方式,收集真實情境中的交際障礙案例，並依據跨文化溝通能力指標，設計以跨文化溝通為導向的華語教材。並在海外針對華語二語學習者提供教材分享，探討如何能透過這套教材，即早預知和理解可能面對因為文化差異所造成的困難，達到與台灣人得體溝通交際的目的。
二語學習除了主要的目標語（target language）語言本體的學習，也應學習目標語的文化（target language culture）。因為跨文化的溝通交際是立基於語言和文化的理解，缺乏任何一項，都可能造成溝通交際的阻礙或誤解。
有別於一般華語教材以語言本體為主要學習目標，本文以目標語地--臺灣的外籍生跨文化溝通的需求為教材設計的依據，採用質化分析與文獻探討的方式,收集真實情境中的交際障礙案例，並依據跨文化溝通能力指標，設計以跨文化溝通為導向的華語教材。並在海外針對華語二語學習者提供教材分享，探討如何能透過這套教材，即早預知和理解可能面對因為文化差異所造成的困難，達到與台灣人得體溝通交際的目的。
Sunday, April 10, 2022
041622 熱帶大氣和颱風的簡化模型
Title:
熱帶大氣和颱風的簡化模型
熱帶大氣和颱風的簡化模型
Time:
Taipei, Taiwan Sun, Apr 17, 2022 at 9:00 am CST
Los Angeles, USA Sat, Apr 16, 2022 at 6:00 pm PDT
Boulder, USA Sat, Apr 16, 2022 at 7:00 pm MDT
Dallas, USA Sat, Apr 16, 2022 at 8:00 pm CDT
Ann Arbor, USA Sat, Apr 16, 2022 at 9:00 pm EDT
Berlin, Germany Sun, Apr 17, 2022 at 3:00 am CEST
Taipei, Taiwan Sun, Apr 17, 2022 at 9:00 am CST
Los Angeles, USA Sat, Apr 16, 2022 at 6:00 pm PDT
Boulder, USA Sat, Apr 16, 2022 at 7:00 pm MDT
Dallas, USA Sat, Apr 16, 2022 at 8:00 pm CDT
Ann Arbor, USA Sat, Apr 16, 2022 at 9:00 pm EDT
Berlin, Germany Sun, Apr 17, 2022 at 3:00 am CEST
Keywords:
Applied Mathematics, Atmospheric Sciences, Moist Convection, Tropical Cyclones, Fluid Dynamics, Fluid Dynamics, Computational Fluid Dynamics, Atmospheric Dynamics, High Performance Computing, Moist Convection, Tropical Cyclone
Applied Mathematics, Atmospheric Sciences, Moist Convection, Tropical Cyclones, Fluid Dynamics, Fluid Dynamics, Computational Fluid Dynamics, Atmospheric Dynamics, High Performance Computing, Moist Convection, Tropical Cyclone
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Abstract:
熱帶大氣在氣候變遷下的改變，會直接的影響極端天氣事件出現的機會，並對我們的生活造成影響。儘管熱帶大氣已經被研究超過百年，仍然存在許多不確定因素，其中水氣為主要的來源。本次演講將介紹熱帶大氣的動力、熱力結構和平衡狀態，以及對流產生的條件和扮演的角色，並利用簡化的狀態方程式來進行數學建模。在我們的模型中，簡化了水氣相變的潛熱釋放，並重建熱帶大氣中扮演重要角色的條件不穩定大氣，意即未凝結的空氣塊是對流穩定；而凝結的空氣塊是對流不穩定的。在模擬中，我們找到類似颱風的渦旋，代表許多過去文獻中形成颱風的條件可能是非必要，值得我們更深入去瞭解物理過程在熱帶大氣中所扮演的角色。
熱帶大氣在氣候變遷下的改變，會直接的影響極端天氣事件出現的機會，並對我們的生活造成影響。儘管熱帶大氣已經被研究超過百年，仍然存在許多不確定因素，其中水氣為主要的來源。本次演講將介紹熱帶大氣的動力、熱力結構和平衡狀態，以及對流產生的條件和扮演的角色，並利用簡化的狀態方程式來進行數學建模。在我們的模型中，簡化了水氣相變的潛熱釋放，並重建熱帶大氣中扮演重要角色的條件不穩定大氣，意即未凝結的空氣塊是對流穩定；而凝結的空氣塊是對流不穩定的。在模擬中，我們找到類似颱風的渦旋，代表許多過去文獻中形成颱風的條件可能是非必要，值得我們更深入去瞭解物理過程在熱帶大氣中所扮演的角色。
Sunday, April 3, 2022
040922 How Imprecise Channel Knowledge Can Affect the Fundamental Limits of Wireless Network
Title:
How Imprecise Channel Knowledge Can Affect the Fundamental Limits of Wireless Network
How Imprecise Channel Knowledge Can Affect the Fundamental Limits of Wireless Network
Time:
04/09 (Sat.) 7:00 pm PDT, 8:00 pm MDT, 9:00 pm CDT, 10:00 pm EDT
04/10 (Sun.) 4:00 am CEST, 10:00 am Taiwan
Time zone conversion tool
04/09 (Sat.) 7:00 pm PDT, 8:00 pm MDT, 9:00 pm CDT, 10:00 pm EDT
04/10 (Sun.) 4:00 am CEST, 10:00 am Taiwan
Time zone conversion tool
Keywords:
Electrical Engineering, Telecommunications and Networking/Information Theory, 傳送端通道狀態資訊（Channel State Information at Transmitters）, 網路容量（Network Capacity）, 廣義自由度（Generalized Degress of Freedom）, 廣播通道（Broadcast Channels）, 極網理論（Extremal Network Theory）
Electrical Engineering, Telecommunications and Networking/Information Theory, 傳送端通道狀態資訊（Channel State Information at Transmitters）, 網路容量（Network Capacity）, 廣義自由度（Generalized Degress of Freedom）, 廣播通道（Broadcast Channels）, 極網理論（Extremal Network Theory）
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Abstract:
今日無線網路能同時不間斷傳輸影音給多人，仰賴有效管理無線訊號干擾。訊號經傳播而衰減扭曲，若在傳送端事先知道傳播效果，便可調整傳輸方式，減低網內互打的干擾，提升網路傳輸效能。傳播效果又稱「通道狀態資訊」（Channel State Information），資訊失真程度如何影響效能極限，是近二十年來網路消息理論焦點課題之一。
在本次分享中，我將介紹此課題近 五年來之突破。首先以有線傳輸通道為例，介紹消息理論的分析架構、效能極限，以及其為現代無線網路之發展所帶來之影響。接著延伸至無線網路，介紹其在完整通道狀態資訊下，效能極限之部分成果與待解問題。最後介紹通道資訊失真下，近五年學界研究成果：若資訊精度略有不足，無線網路之效能極限與完整資訊相比，存在巨大差異；我們利用分析上述問題而發展的「對齊映像不等式」（Aligned Image Bounds），進一步量化在通道資訊精度不足下，大型網路的效能極限。
今日無線網路能同時不間斷傳輸影音給多人，仰賴有效管理無線訊號干擾。訊號經傳播而衰減扭曲，若在傳送端事先知道傳播效果，便可調整傳輸方式，減低網內互打的干擾，提升網路傳輸效能。傳播效果又稱「通道狀態資訊」（Channel State Information），資訊失真程度如何影響效能極限，是近二十年來網路消息理論焦點課題之一。
在本次分享中，我將介紹此課題近 五年來之突破。首先以有線傳輸通道為例，介紹消息理論的分析架構、效能極限，以及其為現代無線網路之發展所帶來之影響。接著延伸至無線網路，介紹其在完整通道狀態資訊下，效能極限之部分成果與待解問題。最後介紹通道資訊失真下，近五年學界研究成果：若資訊精度略有不足，無線網路之效能極限與完整資訊相比，存在巨大差異；我們利用分析上述問題而發展的「對齊映像不等式」（Aligned Image Bounds），進一步量化在通道資訊精度不足下，大型網路的效能極限。
Tuesday, March 22, 2022
032722 親職倦怠的文化研究：理論與應用
Title:
親職倦怠的文化研究：理論與應用
親職倦怠的文化研究：理論與應用
Time:
03/27 (Sun.) 6:30 am PDT, 7:30 am MDT, 8:30 am CDT, 9:30 am EDT, 3:30 pm CEST, 9:30 pm Taiwan
Time zone conversion tool
03/27 (Sun.) 6:30 am PDT, 7:30 am MDT, 8:30 am CDT, 9:30 am EDT, 3:30 pm CEST, 9:30 pm Taiwan
Time zone conversion tool
Keywords:
psychology, clinical psychology, culture, perfectionism, individualism, emotion regulation, parenting stress
psychology, clinical psychology, culture, perfectionism, individualism, emotion regulation, parenting stress
Abstract:
There could be as high as 8% of parents suffering from parental burnout—a chronic stress-related disorder experienced in the parental role. It is worrying because parental burnout jeopardizes both parental (e.g., suicidal ideations) and children’s (e.g., depression) adjustment. As regards its etiological antecedents, Western culture seems to play a crucial role: Western parents are five times more vulnerable to parental burnout than parents in the rest of the world. But why parents in the West are especially vulnerable to parental burnout? What factors shared by these communities can explain such an association?
To answer these questions, the present research focused on cultural factors and utilized both a top-down (i.e., with a priori hypotheses) and bottom-up (i.e., without a priori hypotheses) approach to examine which and how Western cultural factors predispose parents to parental burnout. Based on these findings, we further proposed and verified how to protect parents from parental burnout.
There could be as high as 8% of parents suffering from parental burnout—a chronic stress-related disorder experienced in the parental role. It is worrying because parental burnout jeopardizes both parental (e.g., suicidal ideations) and children’s (e.g., depression) adjustment. As regards its etiological antecedents, Western culture seems to play a crucial role: Western parents are five times more vulnerable to parental burnout than parents in the rest of the world. But why parents in the West are especially vulnerable to parental burnout? What factors shared by these communities can explain such an association?
To answer these questions, the present research focused on cultural factors and utilized both a top-down (i.e., with a priori hypotheses) and bottom-up (i.e., without a priori hypotheses) approach to examine which and how Western cultural factors predispose parents to parental burnout. Based on these findings, we further proposed and verified how to protect parents from parental burnout.
Tuesday, March 15, 2022
031922 香港反送中之後，影像如何記錄這個時代？淺談《不割席》、《暗夜星辰》中的情感政治
Title:
香港反送中之後，影像如何記錄這個時代？淺談《不割席》、《暗夜星辰》中的情感政治
香港反送中之後，影像如何記錄這個時代？淺談《不割席》、《暗夜星辰》中的情感政治
Time:
03/19 (Sat.) 6:00 pm PST, 7:00 pm MST, 8:00 pm CST, 9:00 pm EST
03/20 (Sun.) 2:00 am CET, 9:00 am Taiwan
Time zone conversion tool
03/19 (Sat.) 6:00 pm PST, 7:00 pm MST, 8:00 pm CST, 9:00 pm EST
03/20 (Sun.) 2:00 am CET, 9:00 am Taiwan
Time zone conversion tool
Keywords:
傳播學, 文化研究, 性別與傳播科技, 電影研究, 時代革命, 香港反送中, 香港紀錄片
傳播學, 文化研究, 性別與傳播科技, 電影研究, 時代革命, 香港反送中, 香港紀錄片
本次演講未提供錄影
Abstract:
自2019年反送中運動後，相關紀錄片也相繼上映。本文主要探討兩部立場截然不同的反送中紀錄片，分別是《不割席》（Do Not Split）及《暗夜星辰》（Starry Night）。前者為挪威導演Anders Hammer的短片，入圍第九十三屆「奧斯卡最佳紀錄短片」，然卻因觸及敏感的政治因素無法在香港轉播頒獎典禮。《不割席》所代表的為香港抗爭者們的立場，該紀錄片中拍攝了大量示威者抗爭時的畫面，並對這些擁有不同主張的抗爭者進行訪問。後者為香港警務處、鳳凰衛視出品的《暗夜星辰》，主打以「另一個視角看帶反送中」，從警隊的視角出發，全片主打溫情牌，彰顯警方在此運動中的無奈及所受到的傷害。
於此，本研究主要討論三個面向：1.在九七年後，香港電影產業緊縮如何促成獨立紀錄片的發展？而獨立紀錄片如何作為日後香港研究中的重要取徑；2.在這兩部截然不同的紀錄片中，其相互指控的「暴力他者」是如何被建構而出的；3.在社運過後，抗爭者們如何在創傷經驗中開展希望政治。
本場演講參與者都可以免費領取到限量NFT參加證明，有興趣的人請先在手機上安裝 POAP App (按此下載)
自2019年反送中運動後，相關紀錄片也相繼上映。本文主要探討兩部立場截然不同的反送中紀錄片，分別是《不割席》（Do Not Split）及《暗夜星辰》（Starry Night）。前者為挪威導演Anders Hammer的短片，入圍第九十三屆「奧斯卡最佳紀錄短片」，然卻因觸及敏感的政治因素無法在香港轉播頒獎典禮。《不割席》所代表的為香港抗爭者們的立場，該紀錄片中拍攝了大量示威者抗爭時的畫面，並對這些擁有不同主張的抗爭者進行訪問。後者為香港警務處、鳳凰衛視出品的《暗夜星辰》，主打以「另一個視角看帶反送中」，從警隊的視角出發，全片主打溫情牌，彰顯警方在此運動中的無奈及所受到的傷害。
於此，本研究主要討論三個面向：1.在九七年後，香港電影產業緊縮如何促成獨立紀錄片的發展？而獨立紀錄片如何作為日後香港研究中的重要取徑；2.在這兩部截然不同的紀錄片中，其相互指控的「暴力他者」是如何被建構而出的；3.在社運過後，抗爭者們如何在創傷經驗中開展希望政治。
本場演講參與者都可以免費領取到限量NFT參加證明，有興趣的人請先在手機上安裝 POAP App (按此下載)
Tuesday, March 8, 2022
031222 創造力的判斷與雜訊
Title:
創造力的判斷與雜訊
創造力的判斷與雜訊
Speaker:
Time:
03/12 (Sat.) 5:00 pm PST, 6:00 pm MST, 7:00 pm CST, 8:00 pm EST
03/13 (Sun.) 2:00 am CET, 9:00 pm Taiwan
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03/12 (Sat.) 5:00 pm PST, 6:00 pm MST, 7:00 pm CST, 8:00 pm EST
03/13 (Sun.) 2:00 am CET, 9:00 pm Taiwan
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Keywords:
組織行為, 創造力
組織行為, 創造力
本次演講未提供錄影
Abstract:
判斷創新產品是否暢銷已經成為時下熱門的議題，然而在做決策時，我們經常受到不相干的預測因子，影響了我們對於創新產品的判斷力，本研究試圖採用最新的決策理論以及自然語言處理技術，對於創新產品可以達到更高品質更好的判斷力。
Sunday, February 27, 2022
030522 為你養一頭牛：芻料燕麥的遺傳研究
Title:
為你養一頭牛：芻料燕麥的遺傳研究
Time:
03/05 (Sat.) 4:00 pm PST, 5:00 pm MST, 6:00 pm CST, 7:00 pm EST
03/06 (Sun.) 01:00 am CET, 08:00 am Taiwan
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03/05 (Sat.) 4:00 pm PST, 5:00 pm MST, 6:00 pm CST, 7:00 pm EST
03/06 (Sun.) 01:00 am CET, 08:00 am Taiwan
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Keywords:
genetics, plant science, molecular biology, bioinformatics, 燕麥; 全基因體關連性分析; 種子活力
genetics, plant science, molecular biology, bioinformatics, 燕麥; 全基因體關連性分析; 種子活力
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Abstract:
種子活力對作物萌芽、產量、品質都有重要影響。優良的種子活力有助提高芻料作物與雜草的競爭優勢、降低田間管理的成本。燕麥（Avena sativa L.）是重要的芻料作物之一，本研究以650個優良燕麥品系及378個燕麥地方品系為材料，以影像分析調查種子活力相關性狀，並藉由全基因體關聯性分析（genome-wide association study）探討其遺傳結構。結果發現大部分的性狀有相當大的變異，且近似常態分布。分析發現42與17個分子標誌分別與根及芽的相關性狀有顯著關聯性。其中4個標誌位在已知的基因序列中。相關的基因功能與木膠的生合成及植物的苗期生長有關，值得進一步研究。
種子活力對作物萌芽、產量、品質都有重要影響。優良的種子活力有助提高芻料作物與雜草的競爭優勢、降低田間管理的成本。燕麥（Avena sativa L.）是重要的芻料作物之一，本研究以650個優良燕麥品系及378個燕麥地方品系為材料，以影像分析調查種子活力相關性狀，並藉由全基因體關聯性分析（genome-wide association study）探討其遺傳結構。結果發現大部分的性狀有相當大的變異，且近似常態分布。分析發現42與17個分子標誌分別與根及芽的相關性狀有顯著關聯性。其中4個標誌位在已知的基因序列中。相關的基因功能與木膠的生合成及植物的苗期生長有關，值得進一步研究。
Monday, February 14, 2022
021922 A Novel Energy-efficient Process of Converting CO2 to Dimethyl Ether with Techno-economic and Environmental Evaluation
Title:
021922 A Novel Energy-efficient Process of Converting CO2 to Dimethyl Ether with Techno-economic and Environmental Evaluation
021922 A Novel Energy-efficient Process of Converting CO2 to Dimethyl Ether with Techno-economic and Environmental Evaluation
Time:
02/19 (Sat.) 7:00 pm PST, 8:00 pm MST, 9:00 pm CST, 10:00 pm EST
02/20 (Sun.)4:00 am CET, 11:00 am Taiwan
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02/19 (Sat.) 7:00 pm PST, 8:00 pm MST, 9:00 pm CST, 10:00 pm EST
02/20 (Sun.)4:00 am CET, 11:00 am Taiwan
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Keywords:
chemical engineering, process systems engineering, Dimethyl Ether, CO2 Utilization, PTL, Alternative Fuel, Process Intensification
chemical engineering, process systems engineering, Dimethyl Ether, CO2 Utilization, PTL, Alternative Fuel, Process Intensification
Abstract:
This work aims at discovering the potential of CO2 reduction by implementing techniques of process intensification in the production processes of green alternative fuel, dimethyl ether (DME), from CO2 and renewable hydrogen (H2) with both one-step and two-step configurations. A novel intensified process using the two-step configuration (named as TSHI), which converts CO2 to methanol followed by the dehydration of methanol to DME, is proposed in this study. Developed based on the validated thermodynamic representation and the reaction kinetics expression, TSHI shows the greatest potential of CO2 reduction – 1.704 ton CO2 / ton DME – among the five discussed process scenarios. Though TSHI exhibits high capability of reducing CO2 amount in the atmosphere, the result of techno-economic analysis showed that there are still rooms for further improvements to produce green alternative fuel cost-effectively.
This work aims at discovering the potential of CO2 reduction by implementing techniques of process intensification in the production processes of green alternative fuel, dimethyl ether (DME), from CO2 and renewable hydrogen (H2) with both one-step and two-step configurations. A novel intensified process using the two-step configuration (named as TSHI), which converts CO2 to methanol followed by the dehydration of methanol to DME, is proposed in this study. Developed based on the validated thermodynamic representation and the reaction kinetics expression, TSHI shows the greatest potential of CO2 reduction – 1.704 ton CO2 / ton DME – among the five discussed process scenarios. Though TSHI exhibits high capability of reducing CO2 amount in the atmosphere, the result of techno-economic analysis showed that there are still rooms for further improvements to produce green alternative fuel cost-effectively.
Monday, February 7, 2022
021222 Persuasion, Strategic News Sharing, and Cascades on Social Networks
Title:
Persuasion, Strategic News Sharing, and Cascades on Social Networks
Persuasion, Strategic News Sharing, and Cascades on Social Networks
Time:
02/12 (Sat.) 11 am PST, 12 pm MST, 1 pm CST, 2 pm EST, 8 pm CET
02/13 (Sun.) 3 am Taiwan
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02/12 (Sat.) 11 am PST, 12 pm MST, 1 pm CST, 2 pm EST, 8 pm CET
02/13 (Sun.) 3 am Taiwan
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Keywords:
Economics, Game Theory, Network Economics, Information Economics, Persuasion, Strategic News Sharing, Spread of Information, Social Networks
Economics, Game Theory, Network Economics, Information Economics, Persuasion, Strategic News Sharing, Spread of Information, Social Networks
Abstract:
We develop a game-theoretic model of sharing decisions among online users of a Twitter-like social network. Each agent has a subjective prior on an unobservable real-valued state. When receiving news, agents make a decision as to whether they should share the news with their followers based on how persuasive the news may be in moving their followers’ opinions closer to theirs, assuming a nominal cost for sharing. We characterize the dynamics of spread as an endogenous Susceptible-Infected (SI) epidemic process and derive agents’ sharing decisions and the size of the cascade spread at the equilibrium of the corresponding game. We show that low credibility news can result in a larger cascade than credible news when the network is highly connected. We further show that increased polarization in prior beliefs in the population prompts more sharing of lower credibility news, resulting in larger cascade size. Finally, we fully characterize the relationship between cascade size, network connectivity, and news credibility in terms of polarization and diversity of prior beliefs. Our results provide a theoretical foundation for recent empirical observations demonstrating faster and wider spread of low-credibility and false information on social networks. This is a joint work with Amir Ajorlou and my advisor Ali Jadbabaie.
We develop a game-theoretic model of sharing decisions among online users of a Twitter-like social network. Each agent has a subjective prior on an unobservable real-valued state. When receiving news, agents make a decision as to whether they should share the news with their followers based on how persuasive the news may be in moving their followers’ opinions closer to theirs, assuming a nominal cost for sharing. We characterize the dynamics of spread as an endogenous Susceptible-Infected (SI) epidemic process and derive agents’ sharing decisions and the size of the cascade spread at the equilibrium of the corresponding game. We show that low credibility news can result in a larger cascade than credible news when the network is highly connected. We further show that increased polarization in prior beliefs in the population prompts more sharing of lower credibility news, resulting in larger cascade size. Finally, we fully characterize the relationship between cascade size, network connectivity, and news credibility in terms of polarization and diversity of prior beliefs. Our results provide a theoretical foundation for recent empirical observations demonstrating faster and wider spread of low-credibility and false information on social networks. This is a joint work with Amir Ajorlou and my advisor Ali Jadbabaie.
Tuesday, January 18, 2022
220122 Jupyter Meets the Earth：量身打造地科研究的軟體生態系
Title:
Jupyter Meets the Earth：量身打造地科研究的軟體生態系
Jupyter Meets the Earth：量身打造地科研究的軟體生態系
Time:
01/22 (Sat.) 6 pm PST, 7 pm MST, 8 pm CST, 9 pm EST
01/23 (Sun.) 3 am CET, 10 am Taiwan
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01/22 (Sat.) 6 pm PST, 7 pm MST, 8 pm CST, 9 pm EST
01/23 (Sun.) 3 am CET, 10 am Taiwan
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Keywords:
Earth science, data science, cryosphere science, remote sensing, atmospheric science, Jupyter, Earth science, science communication, research, education
Earth science, data science, cryosphere science, remote sensing, atmospheric science, Jupyter, Earth science, science communication, research, education
Abstract:
隨著地球科學的觀測資料與速度日漸提升，地科研究的社群正面臨許多新挑戰，包括如何在有限的時間內獲取並分析不同尺度的資料、交流最新的研究方法、重現研究成果，以及如何讓論文讀者更有效率的吸收知識等等。Jupyter meets the Earth 計畫團隊包含了地球科學研究者和資料科學工作者，我們以軟體開發的角度解決上述問題，採用研究者的即時回饋設計基於 Jupyter 的開源研究工具。我會從幾個活躍的使用例出發，包括大氣科學、遙測與冰雪圈研究，分享新的 Jypyter 生態系如何改善地科研究的效率，並增強科研與教育工作者、產業與社會大眾的交流。
隨著地球科學的觀測資料與速度日漸提升，地科研究的社群正面臨許多新挑戰，包括如何在有限的時間內獲取並分析不同尺度的資料、交流最新的研究方法、重現研究成果，以及如何讓論文讀者更有效率的吸收知識等等。Jupyter meets the Earth 計畫團隊包含了地球科學研究者和資料科學工作者，我們以軟體開發的角度解決上述問題，採用研究者的即時回饋設計基於 Jupyter 的開源研究工具。我會從幾個活躍的使用例出發，包括大氣科學、遙測與冰雪圈研究，分享新的 Jypyter 生態系如何改善地科研究的效率，並增強科研與教育工作者、產業與社會大眾的交流。
Sunday, January 2, 2022
220108 Re-Examine Musculoskeletal Disease by Deep Learning
Title:
Re-Examine Musculoskeletal Disease by Deep Learning
Re-Examine Musculoskeletal Disease by Deep Learning
Time:
01/08 (Sat.) 8 pm PST, 9 pm MST, 10 pm CST, 11 pm EST
01/09 (Sun.) 5 am CET, 12 pm Taiwan
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01/08 (Sat.) 8 pm PST, 9 pm MST, 10 pm CST, 11 pm EST
01/09 (Sun.) 5 am CET, 12 pm Taiwan
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Keywords:
Medical Images, Deep Learning, Osteoarthritis, MRI, Deep generative Models
Medical Images, Deep Learning, Osteoarthritis, MRI, Deep generative Models
為配合本研究發表時程，本次錄影將延遲上傳
Abstract:
The management of degenerative and age-related diseases are expected to be one of the prominent challenges to Taiwan’s medical system as the population ages. Osteoarthritis (OA) is one of the most prevalent and debilitating degenerative and age-related diseases, with its burden expected to increase by several folds around the globe due to population aging and risks factors such as increasing rates of obesity. Deep learning-based imaging biomarkers provide great promise in specifying novel treatments target, facilitating new strategies of early detection and prevention techniques, and identifying population that is vulnerable to disease progression and disability. It is therefore of great importance to explore these new opportunities to alleviate the burden of OA and other age-related musculoskeletal diseases, especially in an aging society of Taiwan. In this talk, we will cover our efforts to study morphological biomarkers of early OA and onset of OA by performing automatic knee MRI segmentation across various population and development of the explainable AI models to identify potential target of treatment of reducing osteoarthritis (OA) pain and minimizing likelihood of surgical intervention.
The management of degenerative and age-related diseases are expected to be one of the prominent challenges to Taiwan’s medical system as the population ages. Osteoarthritis (OA) is one of the most prevalent and debilitating degenerative and age-related diseases, with its burden expected to increase by several folds around the globe due to population aging and risks factors such as increasing rates of obesity. Deep learning-based imaging biomarkers provide great promise in specifying novel treatments target, facilitating new strategies of early detection and prevention techniques, and identifying population that is vulnerable to disease progression and disability. It is therefore of great importance to explore these new opportunities to alleviate the burden of OA and other age-related musculoskeletal diseases, especially in an aging society of Taiwan. In this talk, we will cover our efforts to study morphological biomarkers of early OA and onset of OA by performing automatic knee MRI segmentation across various population and development of the explainable AI models to identify potential target of treatment of reducing osteoarthritis (OA) pain and minimizing likelihood of surgical intervention.
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